Zachary Siegel

While an overdose epidemic tears through the U.S., some users have found that opioids work as antidepressants. Is there a safe way to use them?

The U.S. addiction treatment system is so broken that drug users rely on festive raffles, rehab "scholarships" and GoFundMe pages to kick drugs.

While most people on daily meds for chronic conditions don’t think twice about traveling, people who take methadone describe the experience as a stressful, tedious slog that takes weeks of preparation.

Author and professor Eugene Thacker tells us about how pessimism can be a form of self-help.

We looked into the concept of "once an addict, always an addict."

A 1967 Commission on Law Enforcement report on drugs was way ahead of its time.

Based on my experience as a former heroin user, and as a journalist covering addiction, the show’s depiction is refreshingly authentic.

Everything you need to know about buying and using the anti-overdose drug.

While the rest of the world continues to resist.

While America continues to resist.

It's how Switzerland solved its overdose crisis.